What Causes Depression?

The link between the male hormone testosterone and depression is not one usually thought of by men suffering from depression as they tend to believe depression is more psychological and emotional rather than physical. However, depression IS a major health issue that, in many cases, can be directly or indirectly caused by low testosterone levels (Male Hormone Imbalance). Studies show that men with low testosterone levels are 4 times more likely to suffer from depression than men with testosterone levels in the normal range.

The connection between depression and Andropause should come as no surprise considering the number of common symptoms they both possess.

  • Symptons Depression and Male Hormone Imbalance Have in Common

  • Weight gain

  • Irritability

  • Fatigue

  • Decreased Sex Drive

Of course, causes and symptoms can sometimes be interchangeable between certain conditions like Andropause and depression. Some of the symptoms of Male Hormone Imbalance, like weight gain, decreased libido and irritability can go on for extended periods of time, leading to downward changes in mood, which will often lead to full on depression.

Serotonin Levels Can Cause Depression

A more direct cause of depression due to low testosterone is the belief by many in the medical community that decreased testosterone levels will affect the production of another hormone, serotonin. 90% of serotonin is located in the digestive tract and in blood platelets. However, the serotonin produced in the brain relays signals between different parts of the brain. While performing many different psychological functions, one of serotonin’s primary jobs is to regulate our moods. More than 75% of the approximately 40 million cells in the brain are directly or indirectly influenced by serotonin. Like with testosterone, serotonin production tends to decrease as men age.

  • Serotonin’s Effects on a Man’s Mental Health

  • Mood Regulation

  • Influences ¾ of Cells in the brain’

  • Signal Relays to Different Areas of the Brain

  • Regulates Appetite

NuMale Can Help

Studies have shown that as many as half of all men suffering from depression also suffer from low testosterone levels. If a male is suffering from depression AND Male Hormone Imbalance at the same time, testosterone therapy or other male hormone treatments may be safer, more effective and longer lasting than anti-depressant drugs. The bottom line is that men with depression who aren’t responding to anti-depressant medications should have their testosterone levels checked to find out if an alternate course of action might need to be taken.

Men who suffer from depression and aren’t responding to anti-depressant drugs may need to visit to a licensed Male Rejuvenation and Health Facility staffing qualified physicians. When you visit a NuMale medical center, our doctors can have a man’s hormone levels tested to help determine if Male Hormone Imbalance is at the root of their depression. Results usually come on the same visit.

Getting Tested and Treated for Male Hormone Imbalance

Deression caused by Male Hormone Imbalance, is testable, treatable and correctable. Through treatment, depression symptoms will decrease and often disappear, allowing men to be happier and feel better about life.

At NuMale the treatment of choice is Bioidentical Testosterone Replacement Therapy. The term bioidentical means the testosterone being used will be an exact match of the hormone produced in the male body in chemical makeup and molecular structure. Bioidentical Testosterone Replacement Therapy involves putting testosterone pellets the size of a Tic-Tac under the skin. The pellets slowly dissolve, infusing hormones into the body. This therapy can usually begin the same day of the patient’s first visit after their testosterone and estrogen levels are tested. The procedure is a quick, painless in-office procedure with effects that are felt within days and results that last 5-6 months.

Taking the 1st Step

A visit to a NuMale Medical Center to consult with a qualified licensed physician is the best course of action for many men suffering with depression related to Andropause. At our facility men, along with their physician, can discuss the patient’s ongoing symptoms and discuss the best form of treatment to combat depression and its symptoms. Each treatment plan will be tailored to the individual patient’s needs as no two cases are alike.


If you are a male and suffering from this or any other men’s health issue and believe NuMale Medical Clinic could help, please click on the Get Price Now tab of this website to set up an initial consultation with one of our licensed Men’s Health Physicians. Appointments can also be scheduled by phone by dialing (866) 205-8262.  Our experts will work with you one-on-one to determine the optimal course of treatment to correct your condition.


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